Immunopathogenesis of conjunctival remodelling in vernal keratoconjunctivitis
نویسندگان
چکیده
منابع مشابه
Conjunctival expression of thymosin-beta4 in vernal keratoconjunctivitis.
PURPOSE Thymosin-beta4 (Tbeta4) is a small actin-sequestrating peptide that modulates inflammation and healing in different tissues. The aim of this study was to investigate the molecular and biochemical expression of Tbeta4 in the healthy conjunctiva and in the conjunctiva of patients with vernal keratoconjunctivitis (VKC), a severe allergic eye disease characterized by chronic inflammation an...
متن کاملConjunctival Inclusion Cysts in Long-standing Chronic Vernal Keratoconjunctivitis
PURPOSE To report a case of conjunctival inclusion cysts on the corneal limbus of a patient with chronic vernal keratoconjunctivitis during 16 months' follow up. METHODS The patient was a 26 year old male without any specific history of surgery or trauma. Giant papillae, shield ulcers, and Horner-Trantas dots were detected. During the 16 month follow-up, Sodium cromoglycate eye drops and Pred...
متن کاملVernal keratoconjunctivitis
Vernal keratoconjunctivitis (VKC) is a chronic allergic conjunctivitis that is most often seen in young, males. Although most types of allergic conjunctivitis do not affect vision, VKC is unusual in that damage to the cornea from the condition can result in vision loss. Although it is typically seasonal, year-round symptoms can be seen, which can lead to uncertain diagnoses being made. Although...
متن کاملManagement of Vernal Keratoconjunctivitis
Vernal keratoconjunctivitis (VKC) is a relatively rare, chronic form of ocular allergy that can potentially cause severe visual complications. Affecting mainly children and young adults, it is an IgE- and T cell-mediated disease, leading to a chronic inflammation in which eosinophil, lymphocyte and structural cell activation are involved. Treatment of VKC requires a multiple approach that inclu...
متن کاملAdhesion molecules in vernal keratoconjunctivitis.
AIMS/BACKGROUND Adhesion molecules play a key role in the selective recruitment of different leucocyte population to inflammatory sites. The purpose of the present study was to investigate the presence and distribution of adhesion molecules in the conjunctiva of patients with vernal keratoconjunctivitis (VKC). METHODS The presence and distribution of adhesion molecules were studied in 14 conj...
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ژورنال
عنوان ژورنال: Eye
سال: 2005
ISSN: 0950-222X,1476-5454
DOI: 10.1038/sj.eye.6701811